AMELIORATION OF OBSESSIVE-COMPULSIVE DISORDER BY INTRACELLULAR ACIDIFICATION OF CORTICAL NEURONS WITH A PROTON PUMP INHIBITOR

Amelioration of obsessive-compulsive disorder by intracellular acidification of cortical neurons with a proton pump inhibitor

Abstract Obsessive-compulsive disorder (OCD) is a highly prevalent neuropsychiatric disorder poorly controlled with pharmacological treatment because of the wide variation in symptom patterns.We analysed real-world data on adverse self-reports and insurance claims to WATERMELON identify a novel therapeutic target for OCD.We found that dopamine D2 r

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Precise Optical Modeling of Phosphor-Converted LEDs With Arbitrary Concentration and Thickness Using Bidirectional Scattering Distribution Function

Phosphor-converted light-emitting diode (pcLED) is one of the most promising methods to generate white light.The interaction of the excitation light with the phosphor in pcLED is a complicated phenomenon, combining light absorption, light conversion, and scattering.An effective and efficient way to predict the optical behavior of pcLED is using the

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Comparative analysis of greywater pollutant removal efficiency with horizontal free water surface flow wetland with other wetland technologies

The reuse of treated wastewater for agriculture and other purposes is globally recognized as a reliable water source.Constructed wetlands are cost-effective and reliable green technologies for wastewater treatment, offering an environmentally friendly and affordable solution with minimal operational and maintenance requirements.This study assessed

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